Indications of Tofacitinib

1 Rheumatoid Arthritis  

Tofacitinib is indicated for the treatment of adult patients with moderately to  severely active rheumatoid arthritis (RA) who have had an inadequate response or intolerance to  one or more TNF blockers.

2 Psoriatic Arthritis  

Tofacitinib is indicated for the treatment of adult patients with active psoriatic  arthritis (PsA) who have had an inadequate response or intolerance to one or more TNF blockers.

3 Ankylosing Spondylitis  

Tofacitinib is indicated for the treatment of adult patients with active ankylosing spondylitis (AS) who have had an inadequate response or intolerance to one or more TNF blockers.

4 Ulcerative Colitis  

Tofacitinib is indicated for the treatment of adult patients with moderately to  severely active ulcerative colitis (UC), who have an inadequate response or intolerance to one or  more TNF blockers.

5 Polyarticular Course Juvenile Idiopathic Arthritis  

Tofacitinib Oral Solution is indicated for the treatment of active polyarticular course  juvenile idiopathic arthritis (pcJIA) in patients 2 years of age and older who have had an  inadequate response or intolerance to one or more TNF blockers.

from FDA，2024.09