Contraindications you must know before using Abrocitinib

Contraindications you must know before using Abrocitinib

Do not use Abrocitinib under the following circumstances: if you are allergic to Abrocitinib or any other ingredients in the medicine; if you have a serious active infection, including tuberculosis; if you have severe liver problems; or if you are pregnant or breastfeeding. If any of these apply to you, be sure to inform your doctor, who will choose an appropriate alternative treatment for you. Additionally, if you have ever had hepatitis B or hepatitis C, please inform your doctor in advance.

Risk of infection and related symptoms to watch for

While using Abrocitinib, you need to be particularly vigilant for various infections. If you experience symptoms such as fever, ulcers, unusual fatigue, or dental problems, contact your doctor immediately, as these could be signs of infection. Special attention should be paid to shingles (herpes zoster). If you have had this condition before, using Abrocitinib may cause it to recur. If you develop a painful blistering rash, seek immediate medical attention. Additionally, your doctor will check for tuberculosis before starting treatment. If you have had close contact with someone with tuberculosis, you should also proactively inform your doctor.

Risk of blood clots, heart problems, cancer, and skin examination recommendations

Abrocitinib may increase the risk of blood clots, particularly deep vein thrombosis in the legs or pulmonary embolism. If you suddenly experience shortness of breath, chest pain, upper back pain, swelling or pain in an arm or leg, or skin discoloration, seek immediate medical attention. If you have a history of blood clots, have recently had major surgery, use hormonal contraceptives, or have a family history of clotting disorders, discuss this thoroughly with your doctor before using this medicine. Furthermore, elderly patients (aged 65 years and older) are at higher risk of heart disease and certain types of cancer. Non-melanoma skin cancer has been observed during use of Abrocitinib, so your doctor may recommend regular skin examinations. If you develop new skin lesions or changes in existing lesions, consult your doctor promptly.