What are the side effects of Sotorasib?

Sotorasib as a targeted therapeutic agent, is hailed as a milestone advancement in the medical field. As one of the pioneering small molecule inhibitors successfully targeting KRAS and entering human clinical development, Sotorasib demonstrates the ability to selectively and irreversibly inhibit the KRAS protein harboring the G12C mutation, thereby exhibiting immense potential in the treatment of malignant diseases such as NSCLC.

What are the side effects of Sotorasib?

According to the label instructions, potential adverse effects associated with Sotorasib encompass but are not limited to the following points. Patients are advised to vigilantly monitor their physiological responses during the course of treatment and seek prompt medical attention should any discomfort arise.

1. Diarrhea

Diarrhea is one of the most prevalent adverse effects associated with Sotorasib. Some patients may experience gastrointestinal symptoms, ranging from increased frequency of bowel movements in milder cases to more severe manifestations such as abdominal pain and dehydration.

2. Musculoskeletal pain

Sotorasib may also induce musculoskeletal discomfort, which can manifest as either mild or severe. For mild discomfort, patients may attempt relief through methods such as rest and heat therapy; for severe discomfort, prompt medical attention should be sought.

3. Nausea

Nausea is a common side effect of Sotorasib, which may potentially impact a patient's appetite and mood. To mitigate the occurrence of nausea, patients may consider consuming light and bland foods prior to medication administration.

Sotorasib, a prescription medication, should be strictly adhered to as directed by healthcare providers, and patients are advised against unauthorized alterations in dosage or administration. Prior to utilization, individuals should familiarize themselves with the prescribed dosage, contraindications, and potential side effects, thereby mitigating the risks associated with indiscriminate medication consumption.

Dosage and administration of Sotorasib

Here is the recommended usage and dosage of Sotorasib. Patients should adhere to their physician's prescription and take the medication as directed and at the specified intervals.

1. Recommended dose

The recommended dosage of Sotorasib is 960mg, to be taken orally once daily. This dosage should be adjusted based on the individual patient's specific circumstances and the advice of the physician. Patients should strictly adhere to the guidance of their healthcare provider and refrain from self-adjusting the medication dosage.

2. When and how to take the drug

Patients should take Sotorasib at the same time each day, with or without food. It is important for patients to swallow the tablet whole and not chew, crush, or split it during administration.

[Warm tips] Patients undergoing treatment with Sotorasib should undergo regular examinations and evaluations by their physicians to stay abreast of their medical condition and medication efficacy. It is imperative for patients to maintain a healthy lifestyle and mindset during treatment, while actively adhering to their physician's therapeutic advice in order to expedite their recovery.