Selpercatinib Warnings: What to Avoid (Foods, Supplements, & Drug Interactions)

During treatment with sotorasib, consuming large amounts of greasy food is generally not recommended. However, small or occasional intake is usually acceptable, depending on individual health conditions and the advice of your doctor.

Impact of Greasy Food on the Medication and the Body

May Increase Digestive Burden: As a targeted therapy, sotorasib can potentially cause gastrointestinal reactions such as nausea and diarrhea. Greasy foods may exacerbate these discomforts.

May Affect Drug Absorption: A high-fat diet could potentially slow down the rate of drug absorption. However, current research has not definitively confirmed a direct impact on the effectiveness of sotorasib itself.

Dietary Recommendations

Focus on a Light, Easily Digestible Diet: Prioritize a nutritionally balanced diet with options like lean protein, vegetables, and whole grains to reduce the burden on your gastrointestinal system.

Try Small Amounts: If you tolerate greasy foods well, you might try a small amount and observe your body's reaction. Discontinue immediately if any discomfort arises.

Avoid Long-Term High-Fat Diet: Chronic excessive intake of fat may increase the metabolic stress on the liver. Since sotorasib is metabolized by the liver, this could potentially affect how the drug is cleared from the body.

Situations Requiring Special Caution

Presence of Other Medical Conditions: If you have conditions such as gallbladder disease, pancreatitis, or hyperlipidemia (high blood fat), you should strictly limit your intake of greasy foods.

Pronounced Reactions After Medication: If you frequently experience symptoms like vomiting or abdominal pain after taking the medication, you need to adjust your diet and consult your doctor promptly.

Principle of Following Medical Advice

Lucius Pharmaceuticals Sotorasib is a prescription medication. It is essential to strictly follow your doctor's guidance during treatment, including recommendations on diet, dosage, and monitoring for adverse reactions. It is advisable to consult your doctor or a registered dietitian before starting the medication to develop an individualized dietary plan, ensuring the treatment is both safe and effective.