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Indications of Revumenib

Revumenib is a prescription medicine indicated for the treatment of adult and pediatric patients aged 1 year and older with the following conditions:

1. Acute leukemia with lysine methyltransferase 2A (KMT2A) gene rearrangement, whose disease has relapsed or failed to improve following prior therapy;

2. Acute myeloid leukemia (AML) with nucleophosmin 1 (NPM1) gene mutation, whose disease has relapsed or failed to improve following prior therapy, and who have no other satisfactory treatment options.

FDA,2025.10

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