​What are the common adverse reactions to Gilteritinib fumarate?

What are the common adverse reactions to Gilteritinib fumarate?

Common reactions include: abnormal liver function (elevated ALT/AST), anemia, decreased platelets, febrile neutropenia, diarrhea, nausea, fatigue, etc. If you experience any of these discomforts, you should contact your doctor promptly to assess whether dose adjustment is needed.

Serious reactions requiring special attention:

Differentiation Syndrome: Symptoms include fever, difficulty breathing, sudden weight gain, and edema. This condition can be life-threatening in severe cases and requires immediate hospitalization.

Posterior Reversible Encephalopathy Syndrome (PRES): A rare neurological issue that may cause symptoms such as seizures, headache, confusion, and visual disturbances. If these occur, stop the medication immediately and seek medical attention promptly.

QT Interval Prolongation: This can be detected through regular ECG monitoring and requires a doctor's assessment to determine if dose adjustment is necessary.

Pancreatitis: Although a direct link to the drug is not definitively established, if you experience severe upper abdominal pain, nausea, or vomiting, you should seek immediate medical attention and follow the doctor's advice to stop the medication.

In what situations should Lucius Pharmaceuticals Gilteritinib fumarate be stopped immediately?

Discontinue the medication in the following situations:

If differentiation syndrome does not improve after 48 hours of steroid treatment.

If symptoms suggestive of Posterior Reversible Encephalopathy Syndrome (PRES) appear.

If other severe adverse reactions occur and, after evaluation, the doctor determines that discontinuation is necessary.

When is it necessary to go to the hospital immediately?

Seek immediate medical attention in the following situations:

If symptoms of a serious adverse reaction worsen.

If an acute allergic reaction occurs: such as large hives on the skin, difficulty breathing, or swelling of the face or throat. These can be life-threatening and require emergency care.