Which patients are suitable for Revuforj?

Your doctor may prescribe Revuforj tablets in multiple dosage strengths, and it is crucial that you understand how to take the medication correctly. Be sure to know the exact number of tablets you need to take and which dosage strengths they are.

Which patients are suitable for Revuforj?

Relapsed or refractory acute leukemia (R/RAL) with lysine methyltransferase 2A (KMT2A) translocation.

Relapsed or refractory acute myeloid leukemia (R/RAML) with a susceptible nucleophosmin 1 (NPM1) mutation and no other satisfactory treatment options.

Use of Revuforj During Pregnancy and Lactation

Inform your doctor if you are pregnant or planning to become pregnant before taking Revuforj, as it may cause fetal harm. Pregnancy status should be verified within 7 days prior to the initiation of Revuforj treatment for patients of childbearing potential.

Patients of childbearing potential are advised to use effective contraception during Revuforj treatment and for 4 months after the last dose.

Male patients whose partners are of childbearing potential are also advised to use effective contraception during Revuforj treatment and for 4 months after the last dose.

It is unknown whether Revuforj is excreted in human milk. Due to the risk of potential serious adverse reactions in breastfed children, breastfeeding is not recommended during Revuforj treatment and for 1 week after the last dose.

Administration of Revuforj

Take REVUFORJ twice daily on an empty stomach, or with a low-fat meal (e.g., a meal containing approximately 400 calories with ≤25% fat content).

Take REVUFORJ orally at approximately the same time each day.

Patients are advised to swallow the tablets whole; do not cut or chew them. If a patient is unable to swallow the tablets whole, they may be crushed and dispersed in water, and the mixture must be taken within 2 hours of preparation.

If a dose of REVUFORJ is missed or not taken at the usual time, take the missed dose as soon as possible on the same day, at least 12 hours before the next scheduled dose. Resume the normal dosing schedule the following day. Do not take two doses within a 12-hour period.