What drugs does Gilteritinib Fumarate Tablets interact with?

What drugs does Gilteritinib Fumarate Tablets interact with?

Before taking this medication, you must inform your doctor of all medications you are currently using and any health problems you have. Special attention should be paid to interactions with the following three types of drugs:

Strong Enzyme Inducers: Including phenytoin, rifampin, St. John's Wort, etc. These drugs may reduce the effective concentration of this medication in the blood.

Strong Enzyme Inhibitors: Such as voriconazole, itraconazole, clarithromycin, erythromycin (antibiotics and antifungals). These drugs may increase the concentration of this medication in the blood.

Drugs Affecting Specific Receptors: Including antidepressants such as escitalopram, fluoxetine, sertraline. This medication may weaken the therapeutic effect of these drugs.

Dosage and Administration

Use this medication under medical supervision and follow your doctor's instructions. The recommended initial dose is 120mg (equivalent to three 40mg tablets) taken orally once daily. A complete treatment cycle is 28 days. The specific dosing regimen must be strictly followed as prescribed by your doctor.

What is the specific way to use Gilteritinib Fumarate Tablets?

Patients must undergo professional genetic testing before using this medication:

A peripheral blood or bone marrow sample is needed to complete FLT3 gene mutation testing (analyzing for specific genetic abnormalities). This medication is only suitable for patients confirmed to have this gene mutation.

The following details should be noted during treatment:

The medication must be taken under the guidance of a physician experienced in anticancer therapy. The usual starting dose is 120mg per day (equivalent to three 40mg tablets), taken continuously for 28 days, which is considered one complete treatment cycle.

Try to take the medication at the same time each day, either before or after meals. Swallow the tablets whole. Do not split, chew, or crush them.

As long as the patient's condition continues to improve and no severe side effects occur, long-term adherence to the medication is recommended. If you experience intolerable side effects or signs of reduced treatment efficacy, contact your doctor promptly to adjust the plan.

It may take a considerable amount of time for the treatment effect to become apparent. Therefore, even if there is no immediate noticeable improvement, do not stop taking the medication or change the dosage on your own. You must strictly follow the treatment plan prescribed by your doctor.