Side Effects of Ivosidenib

As a targeted therapy, ivosidenib may cause certain side effects while exerting its anti-tumor effects.

Less Severe Side Effects

Common side effects include cracked lips, decreased appetite, diarrhea, difficulty swallowing, nausea, and vomiting.

Severe Side Effects

Common side effects

Black, tarry stools; bleeding gums; blood in the urine or stool; blurred vision; burning, tingling, numbness, or pain in the hands, arms, feet, or legs; chest pain or tightness; chills; confusion; cough; decreased urine output; difficulty or labored breathing; difficulty moving; dizziness, fainting, or lightheadedness when rising suddenly from a lying or sitting position; eye pain; fainting; fever; general feeling of discomfort; headache; arrhythmia (recurrent); joint pain, stiffness, or swelling; lower back, flank, or abdominal pain; muscle pain, cramps, soreness, or stiffness; painful or difficult urination; pale skin; pinpoint red spots on the skin; rapid weight gain; rash; tingling sensation; sore throat; sores, ulcers, or white spots on the lips, tongue, or inside the mouth; stabbing pain; swelling of the arms, feet, or lower legs; unusual bleeding or bruising; unusual tiredness or weakness.

Rare side effects

Inability to move the arms and legs; sudden numbness and weakness in the arms and legs.