What is the recommended dosage for the Lao version of Anagrelide?

Thrombocythemia is a common blood disorder, and drug therapy is one of the common treatments. Among the many drugs, anagrelide is widely used because of its remarkable efficacy. So, to better understand this drug, the first thing we need to focus on is: What is the recommended dosage of Anagrelide?

What is the recommended dosage for the Lao version of Anagrelide?

Anagrelide is a drug used to treat thrombocythemia that helps maintain a normal platelet count by inhibiting the production of platelets in the bone marrow, thereby reducing the risk of thrombosis and improving patient survival. The following are the dosages for anagrelide:

1. For adults, the starting dose of anagrelide is usually 0.5 mg 4 times a day, or 1 mg 2 times a day. The dose can be adjusted after 1 week, but the daily dose can be increased by up to 0.5 mg during the week. The maximum daily dose should not exceed 10 mg, and a single dose should not exceed 2.5 mg.

2. For children over 6 years old, the starting dose is 0.5 mg each time. The dose can be adjusted after 1 week, but the daily dose can be increased by up to 0.5 mg during the week. The maximum daily dose and single dose are the same as for adults.

Patients with hepatic insufficiency may require dose reduction. In addition, patients should follow their doctor's instructions to take their medication accurately and do not change the dosage of the medication or stop using it on their own. Initially, the doctor may adjust the dose based on the patient's response and will need to monitor the patient's platelet count regularly.

The above information is for reference only, please consult a professional doctor or pharmacist if necessary.

What indicators need to be tested while taking the Lao version of Anagrelide

During the period of taking Anagrelide, patients need to monitor a series of indicators regularly. These indicators mainly include the following:

1. Platelet count

Anagrelide is mainly used to treat thrombocythemia, so the number of platelets needs to be monitored regularly, usually weekly during the titration period, and then monthly or as needed. This is useful to assess the effect of the drug on the regulation of platelet production and release.

2. Complete blood count

In addition to platelet count, indicators such as white blood cell count and hemoglobin need to be monitored to get a complete picture of the patient's blood condition.

3. Liver and kidney function assessment

Anagrel may have an effect on liver and kidney function, so it is necessary to regularly monitor liver and kidney function-related indicators, such as aminotransferases, bilirubin, and creatinine.

4. Electrolytes

Electrolyte levels are monitored to assess the effect of medications on electrolyte balance in the body.

5. Cardiovascular-related indicators

Because anagrelide may increase cardiovascular risk, such as QT interval prolongation and increased heart rate, ECGs should be performed regularly and cardiovascular effects monitored.

Following your doctor's advice and having these indicators checked regularly can help patients better manage their disease while reducing the risk of adverse effects.