​What are the Alpelisib side effects?

Alpelisib effectively treats patients with HR/HER2- breast cancer harboring PIK3CA mutations by inhibiting the PI3Kα signaling pathway; The precise targeting effect greatly reduces the proliferation ability of tumor cells, and it has shown good tolerability in clinical practice.

What are the Alpelisib side effects?

During the use of Alpelisib, some side effects may occur. Understanding these side effects can help identify and treat them in a timely manner to ensure a smooth treatment.

1. Elevated creatinine

Drug use may affect renal function, resulting in elevated creatinine levels, suggesting impaired renal filtration and requiring regular monitoring of kidney function.

2. Diarrhea

The medication can cause digestive upset, causing frequent diarrhea that may be accompanied by abdominal pain or stomach upset. Long-term diarrhea can also cause dehydration problems.

With these side effects in mind, let's take a look at the specific usage and dosage recommendations for Alpelisib.

What is the dosage of Alpelisib?

It is important to know the correct dosage and dosage before using Alpelisib.

1. Missed dose

If you miss a dose of Alpelisib, you can take it with a meal within 9 hours of your regular dose. If it is more than 9 hours, skip the dose and take it at the normal time the next day.

2. Time of taking medication

It is recommended to take Alpelisib at the same time every day to help keep the concentration of the drug in the body stable.

After mastering the dosage and dosage of Alpelisib, the next thing to focus on is the medication recommendations for special populations.

Is Alpelisib used for special populations?

Special care should be taken when using Alpelisib in special populations, and treatment regimens should be adjusted on a case-by-case basis.

1. Pregnancy

Animal studies have shown that Alpelisib can be potentially harmful to the fetus, including causing embryonic death, weight loss, and malformations. Specific clinical data for pregnant women are lacking and it is not possible to fully assess the risk of Alpelisib in pregnant women. Pregnant women are advised to avoid the use of this medicine to avoid effects on the fetus.

2. For pediatric patients

The safety and efficacy of Alpelisib in pediatric patients have not been well studied and established. Clinical data are lacking and the use of Alpelisib in children is not recommended.

Medication for special populations should be handled cautiously according to individual conditions, and risks should be fully assessed before medication should be taken, and appropriate precautions should be taken.

[Warm tips] During the use of Alpelisib, please maintain close communication with the medical team, perform necessary examinations regularly, and pay attention to any possible side effects.