​What are the precautions for Alpelisib?

In 2022, Alpelisib received accelerated FDA approval for the treatment of adults and children over 2 years of age on the PIK3CA-associated overgrowth disease spectrum, an expanded indication that further demonstrated efficacy in PI3K inhibition.

What are the precautions for Alpelisib?

Alpelisib plays an important role in the treatment of a wide range of diseases, and precautions during use should also be taken into account.

1. Embryo-fetal toxicity

Women of childbearing potential should use contraception during treatment and for a week after the last dose, and men should use condoms. It is advisable to be aware of the potential risks of the drug to the fetus before treatment.

2. Pneumonia

When new or worsening respiratory symptoms (eg, hypoxia, cough, dyspnea) develop, the drug is stopped immediately and evaluated for pneumonia. After the diagnosis of non-infectious pneumonia, the drug should be permanently discontinued, and changes in respiratory symptoms should be reported.

Patients should read the instructions carefully or consult a doctor for comprehensive information on drug precautions; Next, we will explain the dosage and dosage of the drug.

What are the dosage requirements for Alpelisib?

Before using Alpelisib, it is important to follow your doctor's specific instructions and recommendations for the dosage and dosage requirements of the medicine.

1. Time of taking medication

To ensure the effectiveness of the drug, patients are advised to take Alpelisib at approximately the same time every day. Doing so helps to maintain a stable concentration of the drug in the body, improving the effectiveness and consistency of treatment.

2. How to take medicine

Swallow Alpelisib tablets whole, do not chew, crush or separate. Do not take tablets if they are broken, cracked, or incomplete to avoid affecting the effectiveness of the medicine.

Knowing how to use the drug and how much it is going to do is important for the patient to be treated, and as with other drugs, there are some potential adverse effects that will inevitably occur during the use of Alpelisib.

What are the side effects of Alpelisib?

Alpelisib may cause certain side effects, and attention should be paid to the use of Alpelisib.

1. γ-glutamyl transferase (GGT) is elevated

Medications may cause abnormal liver function, which can increase GGT levels. Regular monitoring of liver function is required to prevent potential liver injury.

2. Nausea

The drug may cause stomach upset, manifested by nausea and vomiting. Long-term nausea may interfere with eating and nutrient intake.

Pay attention to these side effects, communicate with your doctor, and promptly deal with possible abnormal liver function and nausea.

[Warm tips] Take the medicine strictly according to the dosage requirements on the doctor's or drug instructions. Do not increase or decrease the dosage without authorization, as it may affect the effectiveness of the medication or increase the risk of side effects.