What are the side effects of Baloxavir Marboxil (Xofluza)?

Possible Side Effects of Xofluza (Baloxavir Marboxil)

Like all medicines, Xofluza can cause side effects, although not everybody gets them. If you experience any signs of a serious allergic reaction after taking the medicine, such as swelling of the face or skin, an itchy rash, a sudden drop in blood pressure, or difficulty breathing, seek medical attention immediately. The frequency of such severe reactions cannot be estimated from the available data. Other possible side effects include: common side effects (may affect up to 1 in 10 people) are diarrhoea and vomiting; uncommon side effects (may affect up to 1 in 100 people) include an itchy rash. In paediatric patients (aged 3 weeks to less than 12 years), common side effects are diarrhoea, rash, and vomiting. If you experience any suspected adverse reaction not listed in this leaflet, please inform your doctor or pharmacist promptly, and you may also report side effects through official channels.

How to Store Xofluza (Baloxavir Marboxil) Properly?

Keep Xofluza out of the sight and reach of children to avoid accidental ingestion. No special temperature storage conditions are required (i.e., store at room temperature), but protect from moisture: keep the medicine in its original packaging (blister and outer carton), do not open the blister until the time of taking the medicine. Do not use this medicine after the expiry date (EXP) stated on the packaging. The expiry date refers to the last day of that month. The efficacy of expired medicine cannot be guaranteed, and harmful substances may be produced. Do not dispose of unused or expired medicine in household waste or wastewater. Ask your pharmacist how to dispose of medicines properly. For environmental reasons, do not flush any medicine down the toilet or sink or throw it into ordinary household waste.

Special Populations for Xofluza (Baloxavir Marboxil)

Based on available clinical data, the safety of Xofluza in pregnant women has not been established. Animal studies have not shown any evidence of embryotoxicity or teratogenicity, but human pregnancy data are limited. Therefore, to be safe, if you are pregnant, think you may be pregnant, or are planning to become pregnant, avoid using Xofluza. If your influenza is severe and not using an antiviral medicine may pose a greater risk (such as potential harm to the fetus from high fever and pneumonia), your doctor may decide whether to use the medicine after weighing the benefits and risks. Breastfeeding women should also be cautious: it is unknown whether baloxavir marboxil is excreted in human milk. To prevent potential effects on a breastfed infant, it is recommended to temporarily stop breastfeeding during treatment with Xofluza and for several days after the last dose, or to choose a safer alternative antiviral for influenza (such as oseltamivir, for which lactation data are relatively adequate). Please consult your doctor or pharmacist about your specific situation.