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Indications of Alpelisib

Alpelisib is indicated in combination with fulvestrant for the treatment of postmenopausal women, and men,  with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer as detected by an FDA-approved test following progression on or  after an endocrine-based regimen.

from FDA,2022.11

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