Adverse reactions of Ribociclib

In patients with early breast cancer, the most common (incidence ≥ 20%) adverse reactions, including laboratory abnormalities, are lymphocytes  decreased, leukocytes decreased, neutrophils decreased, hemoglobin  decreased, alanine aminotransferase increased, aspartate aminotransferase  increased, infections, creatinine increased, platelets decreased, headache,  nausea, and fatigue. 

In patients with advanced or metastatic breast cancer, the most common  (incidence ≥ 20%) adverse reactions, including laboratory abnormalities, are  leukocytes decreased, neutrophils decreased, hemoglobin decreased,  lymphocytes decreased, aspartate aminotransferase increased, gamma  glutamyl transferase increased, alanine aminotransferase increased,  infections, nausea, creatinine increased, fatigue, platelets decreased, diarrhea, vomiting, headache, constipation, alopecia, cough, rash, back pain,  and glucose serum decreased.

from FDA，2024.09