Who are the indications for Exkivity?

Exkivity offers a new treatment option for NSCLC patients with EGFR exon 20 insertion mutations but should be used with caution and in accordance with professional medical advice.

Who are the indications for Exkivity?

Exkivity is intended primarily for patients with non-small cell lung cancer (NSCLC) with specific gene mutations. Specifically, it is indicated for the treatment of adult patients with locally advanced or metastatic NSCLC who have been genetically tested to carry epidermal growth factor receptor (EGFR) exon 20 insertion mutations.

These mutations are rare in NSCLC patients, accounting for about 5% of patients with EGFR mutations, but Exkivity has shown significant therapeutic efficacy for this specific mutation.

In addition, Exkivity is also indicated for those initially treated patients who have not been previously treated with a MET inhibitor. This means that subject to the above genetic conditions, Exkivity can be used as the treatment of choice for these patients.

What should I pay attention to before using Exkivity?

Before using Exkivity, patients and physicians need to pay attention to the following.

1. Patient-specific conditions

Gene mutation detection: Exkivity is indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) exon 20 insertion mutations. It is important to confirm that the patient has this specific gene mutation before use to ensure that the patient is indeed a good candidate for the drug.

2. Information on drug use

(1) Recommended dose

The recommended dose of Exkivity is 160 mg orally once daily until disease progression or intolerable adverse effects. It should be taken at the same time every day, with or without food.

(2) Dosage

Swallow the capsule whole, and do not open, chew, or dissolve the contents of the capsule.

(3) Treatment of missed doses and vomiting

If the patient misses a dose for more than 6 hours, the missed dose should not be refilled but should be continued at the scheduled time the next day. If the patient vomits after taking the drug, the patient is instructed not to retake the dose but to take the prescribed dose at the scheduled time the next day.

【Warm tips】When patients buy generic drugs, they should choose formal channels to ensure the quality and safety of the drugs. Avoid purchasing counterfeit products from informal sources.