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Therapeutic efficacy of Dacomitinib

ARCHER 1050 demonstrated a statistically significant improvement in PFS as determined by the IRC. Results are summarized in Figures 1 and 2.  

The hierarchical statistical testing order was PFS followed by ORR and then OS. No formal testing of OS was conducted since the formal comparison of ORR was not statistically significant.

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from FDA,2020.12

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