Trelagliptin

Trelagliptin is a drug produced by Takeda Pharmaceutical Co., Ltd. in Japan. It was approved for sale in Japan on March 26, 2015. 

In China, quercetin was first approved for marketing on March 12, 2022, making it the first oral hypoglycemic drug approved for weekly administration in the country.

Trelagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which is a hypoglycemic drug and is mainly used to treat type 2 diabetes. Patients should read the drug instructions carefully before taking the drug to understand the basic information of the drug. The specific method of use and dosage should be carried out according to the specific situation of the patient and the doctor's advice, and do not self-medicate or change the medication regimen.

1.Main components

Trelagliptin

2.Adaptation to the population

Adults with type 2 diabetes

3.Specifications

1. Specifications

Tablets: Takeda, Japan: 100mg*20 tablets, 50mg*20 tablets; Bengal Picon: 100mg*16 tablets; Bengal Yaopin International: 100mg*21 capsules

2. Traits

100mg: is a film-coated tablet with double-sided scribing, and the color is light red.

50mg: is a film-coated tablet with a pale yellowish red color.

4.Medication for special populations

4.1Pregnant and lactating women

Pregnant women or women who may be pregnant, should only use it if the benefits of treatment outweigh the risks. Breastfeeding women need to consider continuing or stopping breastfeeding, considering the benefits of treatment and the benefits of breast milk nutrition.

4.2Children

There are no clinical trials for children.

4.3Elderly

Elderly need to pay attention to side effects, and carefully administer the drug while fully observing the course of the disease, which may cause a decrease in kidney function.

4.4Patients with renal dysfunction

Reduce the dose of patients with moderate or higher renal dysfunction, and carefully observe the patient's condition. Medications are adjusted according to the degree of renal impairment.

4.5Hypoglycemia

If you have pituitary gland insufficiency or adrenal insufficiency, malnutrition, starvation, irregular diet, physical weakness, strenuous exercise, excessive alcohol intake, hypoglycemia may occur, and you should take medication carefully.

4.6Those with a history of abdominal surgery or intestinal obstruction

Those with a history of abdominal surgery or intestinal obstruction are at risk of intestinal obstruction.

5.Drug overdose

An overdose cannot be removed by hemodialysis.

6.Validity period

50mg is valid for 36 months and 100mg is valid for 48 months.

7.Storage methods

Store at room temperature.

8.Pharmacokinetics

A single oral dose of trosagliptin 100 mg 30 minutes before breakfast, and the average plasma concentration was 2.1 ng/mL 168 hours after administration.