What are the side effects of Anamorelin?

Anamorelin is a medication utilized in the treatment of specific ailments, and like all medications, Anamorelin may potentially elicit some adverse effects. Patients should be well informed of these potential side effects before commencing treatment and should use the drug under the guidance of a physician.

What are the side effects of Anamorelin?

According to the label, common side effects of Anamorelin primarily include the following, requiring patients to closely monitor their own reactions and seek prompt medical attention if any discomfort arises.

1. Conduction system inhibition:

Some patients may experience conduction system inhibition after using Anamorelin, potentially resulting in irregular heartbeats or decreased heart rate. It is recommended that patients undergo regular electrocardiogram examinations during the course of treatment.

2. Hyperglycemia and exacerbation of diabetes:

Anamorelin may impact a patient's blood glucose levels, leading to the occurrence of hyperglycemia and potentially exacerbating existing symptoms of diabetes. Diabetic patients should exercise extra caution when using this medication, closely monitoring changes in blood glucose levels.

3. Hepatic impairment:

Anamorelin may also induce certain damage to the liver, causing abnormalities in liver function. Patients undergoing Anamorelin treatment should undergo regular liver function tests to promptly detect and address any potential issues.

Apart from the aforementioned common side effects, Anamorelin may also trigger some less common side effects such as difficulty breathing, pleural effusion, nausea, diarrhea, abdominal pain, decreased muscle strength, and muscle spasms. Despite the rarity of these side effects, patients should remain vigilant and seek immediate medical attention upon the onset of related symptoms.

What are the contraindications of Anamorelin?

Prior to using Anamorelin, patients should take note of the following contraindications:

1. Patients with high-grade conduction disorders:

Patients with conditions such as complete atrioventricular block should refrain from using Anamorelin, as the medication exerts a sodium channel inhibitory effect that may exacerbate symptoms.

2. Patients with drug interactions:

Patients currently taking medications such as clarithromycin, itraconazole, voriconazole, ritonavir-containing preparations, cobicistat-containing preparations, or enzalutamide, which may interact with Anamorelin, should avoid concurrent use to prevent decreased drug efficacy or increased risk of side effects.

3. Patients with moderate to severe hepatic impairment:

Due to the liver's crucial role in the metabolism and excretion of Anamorelin in the body, impaired liver function may lead to drug accumulation, elevated blood drug concentrations, and increased risk of side effects. Patients with moderate to severe hepatic impairment (Child-Pugh class B and C) should exercise caution or avoid the use of this medication.

[Warm tips] While Anamorelin serves in treating ailments, it may also present certain side effects and contraindications. Patients should be thoroughly informed of potential risks and precautions when using this medication and should seek advice from a medical professional if any concerns or discomfort arise.